Is it possible to view custom reports for a custom segment of my users?

Segments will work within you custom reports the same way that work withing the standard Matomo reports. You can apply any of the over 100 segments to custom reports.

Moreover, configuring a custom report allows you to set filters that refine your view of the data. For example, you can select dimensions like “Country” and specify that you want to focus on visitors who accessed your website via a mobile device. This level of detail provides you with a more targeted and insightful analysis.